July 30, 2025
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Great news for older adults! A big new study shows that making healthy lifestyle changes can help keep your brain sharp as you age – even if you’re at risk for Alzheimer’s disease.
What Did Scientists Study?
Researchers did a huge study called the “U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk” (U.S. POINTER). They worked with more than 2,100 people between ages 60-79 at five major universities across the United States.
All the people in the study had things that put them at higher risk for brain problems as they got older:
- They didn’t exercise much (sedentary lifestyle)
- They didn’t eat very healthy diets
- They had heart and metabolism problems
- Someone in their family had memory problems
What Changes Did People Make?
For two years, participants made three main lifestyle changes:
1. Better Eating
People switched from unhealthy diets to something called the MIND diet, which is specially designed to help keep brains healthy. The MIND diet includes:
- Lots of vegetables, especially leafy greens
- Berries and other fruits
- Whole grains
- Fish
- Nuts
- Olive oil
- Limited red meat and processed foods
2. Regular Exercise
Participants had to “get off the couch” and meet fitness goals that included:
- Aerobic exercise (like walking, swimming, or biking to get your heart pumping)
- Resistance exercise (like lifting weights to keep muscles strong)
- Stretching (to keep flexible and prevent injuries)
3. Brain Training
People did daily “cognitive challenges” to exercise their brains, including:
- Using a computer program called BrainHQ training
- Other intellectual activities (like puzzles, reading, or learning new skills)
- Social activities (spending time with other people)
How Were People Supported?
The study had two different groups:
Group 1 – More Structured Program:
- Had 38 meetings with healthcare staff over two years
- Got regular check-ins on their progress
- Had more guidance and support
Group 2 – Self-Directed Program:
- Had only 6 team meetings
- Were encouraged to make “self-selected lifestyle changes that best fit their needs and schedules”
- Had more freedom to choose what worked for them
What Were the Results?
The results were really impressive! Here’s what happened:
People Stuck With It
89% of participants completed the full two-year program. That’s really good – it shows that people were able to make these changes and keep doing them.
Brain Power Improved
Scientists measured something called “global cognitive composite scores” – basically, overall brain health that includes:
- Memory
- Attention
- Language abilities
- Executive function (skills that help you multitask and plan)
The people in the study had statistically significant improvements in their brain scores over the two years.
It Worked for Everyone
Dr. Joanne Pike, president of the Alzheimer’s Association, said the program “was effective across a broad, representative group—regardless of sex, ethnicity, APOE genetic risk or heart health status.”
This means the lifestyle changes helped:
- Both men and women
- People of all ethnic backgrounds
- People with different genetic risks for Alzheimer’s
- People with different levels of heart health
Structured Program Worked Better
People who were in the more structured program (with more meetings and support) saw bigger improvements than those in the self-directed program.
Why Is This Important?
No Medicine Required
One expert pointed out that these brain benefits happened “without the help of any pharmaceuticals.” People improved their brain health just by changing their lifestyle – no drugs needed!
Hope for the Future
Heather Snyder, who helped lead the study, said: “The next generation of treatments for diseases like Alzheimer’s will likely integrate drug and non-drug strategies.”
This means future treatments might combine:
- Healthy lifestyle changes (like in this study)
- Medicine
- Other treatments
A Powerful Public Health Message
Dr. Pike said: “As the burden of dementia grows worldwide, U.S. POINTER affirms a vital public health message: healthy behavior has a powerful impact on brain health.”
What This Means for Older Adults
If you’re over 60 or have family members who are, this study shows that it’s never too late to start taking care of your brain! Even if you have risk factors for memory problems, making healthy changes can help.
The Three Key Areas to Focus On:
1. Eat Brain-Healthy Foods
- Focus on vegetables, fruits, whole grains, fish, and nuts
- Limit processed foods and red meat
- Consider following the MIND diet
2. Stay Physically Active
- Include aerobic exercise (gets your heart pumping)
- Do resistance training (keeps muscles strong)
- Don’t forget stretching
- Find activities you enjoy so you’ll stick with them
3. Exercise Your Brain
- Do puzzles, read books, learn new skills
- Stay socially active – spend time with friends and family
- Consider brain training programs
- Challenge yourself intellectually
Getting Support Helps
The study showed that people did better when they had regular support and check-ins. If you’re trying to make these changes:
- Consider working with healthcare providers
- Join groups or programs focused on healthy aging
- Ask family and friends for support
- Track your progress
The Bottom Line
This study gives us hope that we have more control over our brain health as we age than we might have thought. By making healthy lifestyle changes – eating better, exercising regularly, and keeping our brains active – we can help protect our memory and thinking skills.
The best part? You don’t need expensive medicines or complicated treatments. The tools to keep your brain healthy are things you can start doing today: eat nutritious foods, move your body, challenge your mind, and stay connected with others.
It’s never too late to start taking better care of your brain!
Original article: “Over 60? Healthy lifestyle change may help boost your brain” by Ernie Mundell
Study presented at: The Alzheimer’s Association International Conference in Toronto
Study name: U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk (U.S. POINTER)
